Marine bacteria which produce tetrodotoxin

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Identification of deep-sea-sediment bacteria which produce tetrodotoxin.

Forty-nine bacterial strains were isolated from deep-sea sediments. Among them, 22 strains were shown by the tissue culture assay method to produce sodium channel blockers. For some strains, high-performance liquid chromatography analysis confirmed that the blocker was tetrodotoxin. Tetrodotoxin-producing bacteria seem to be widespread in marine sediment.

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No ability to produce tetrodotoxin in bacteria.

Bacterial production of tetrodotoxin (TTX) was first reported by Yasumoto et al. (8). Detection of bacterially produced TTX has been primarily by high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS). In September 1995, Applied and Environmental Microbiology published a paper indicating that both the HPLC and GC-MS methods lacked specificity for TTX (3)....

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Presence of tetrodotoxin and tetrodotoxin-producing bacteria in freshwater sediments.

The occurrence of tetrodotoxin (TTX) in sediment from Lake Suwa, Japan, was confirmed by a tissue culture assay, high-performance liquid chromatography, and gas chromatography-mass spectrometry. Altogether, 17 TTX-producing bacteria belonging to five genera were isolated from Lake Suwa and Pond Inokasira. Our results indicate that TTX and TTX-producing bacteria occur even in freshwater environm...

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ژورنال

عنوان ژورنال: Applied and Environmental Microbiology

سال: 1987

ISSN: 0099-2240,1098-5336

DOI: 10.1128/aem.53.7.1714-1715.1987